Research that looks at more specific interactions between SNPs and factors like Vitamin E intake, air pollution, exercise or composition of dietary fats is still not that common and tends to be under-powered. One piece of research may appear to settle the question, e.g., a SNP may offer protection against asthma from ozone exposure. But dig a little deeper and one finds results in another study that found the exact opposite, or no association at all. In the early days of personalized genomics, researchers felt optimistic about the quick development of tools for individualized advice. However, in many areas, concrete advice based on genotype has been elusive and more work needs to be done to unravel all the complicated interactions of human biochemistry with the environment. This 2018 paper on precision medicine (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316334/) and Vitamin E dosing says it well, "The core information that exists at present is insufficient to deliver precise recommendations."
Articles in this section
- Why Doesn’t StrateGene Offer More Personalized Supplement and Dosage Suggestions (when Other Companies Do?)
- Why aren't there more precise, individualized recommendations based on genotype for each SNP?
- Why does my report sometimes have factors that slow or speed up genes, like COMT and CYP1A2, but other genes only have factors that clean and dirty them?
- What is the difference between a pharmacological dose and a physiological dose?
- Which products support each StrateGene Pathway?
- What does high estradiol mean?
- I see some commonly mentioned treatments on the internet are not included in StrateGene treatment considerations. Why is this?
- What does time and dose -dependent and habituation mean?
- Why is synthetic folic acid a bad thing?
- What is heme? What are Porphyria or Pyrrole disorders?