This may be explained by phenotype: expression of traits and characteristics that arise with interaction with diet and environment. Phenotype thus differs from genotype which is simply your genetic code, not its subsequent potential expression (phenotype). Perhaps you follow an excellent diet and lifestyle or live in a clean environment that minimizes the effects of the SNP. Many mutations also have low penetrance, meaning few individuals carrying that SNP actually exhibit consequences of the variant. It could also depend on age or other factors: a younger person may not have had time for the consequences to develop into measurable outcomes yet. You can read more here: https://ghr.nlm.nih.gov/primer/inheritance/penetranceexpressivity
Articles in this section
- My notable variation for a haplotype says "indeterminate" - what does this mean?
- How come the StrateGene SNP list is so different from what I am reading elsewhere online?
- How accurate are the COMT Haplotype speeds?
- How important is MAT1A in the SAM/methionine story?
- My COMT speed (specifically V158M/RS4680) was different in a previous StrateGene report than what is being reported here in my new StrateGene. Why is this?
- What does “increased risk” mean?
- How can I find more information about a particular SNP?
- I see results reported as NA, NC, or "indeterminate". What does this mean?
- What is meant by "tag SNP"?
- Why are alleles for SNPs in genes such as SOD2, COMT, and MAO reported differently from other services such as Genetic Genie?