There are many definitions for haplotype, see here for more: https://en.wikipedia.org/wiki/Haplotype. For the purposes of this PDF, a haplotype is a group of single-nucleotide polymorphisms (SNPs) on one chromosome that are statistically shown to be inherited together and are more powerful in providing information about the functionality of an enzyme as compared to looking at a single SNP. Another type of haplotype combines SNPs on different genes and potentially different chromosomes that are inherited more through random chance, but their gene to gene interactions reinforce (for better or worse) a specific outcome.
Articles in this section
- Why Doesn’t StrateGene Report on APOE SNPs?
- My notable variation for a haplotype says "indeterminate" - what does this mean?
- How come the StrateGene SNP list is so different from what I am reading elsewhere online?
- How accurate are the COMT Haplotype speeds?
- How important is MAT1A in the SAM/methionine story?
- My COMT speed (specifically V158M/RS4680) was different in a previous StrateGene report than what is being reported here in my new StrateGene. Why is this?
- What does “increased risk” mean?
- How can I find more information about a particular SNP?
- I see results reported as NA, NC, or "indeterminate". What does this mean?
- What is meant by "tag SNP"?
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