What are the major differences between the old StrateGene Genetic Analysis Tool Report (using 23 and Me or Ancestry) and the new StrateGene Genetic DNA test?

The new StrateGene (test and report) contains updated pathways and explanations of results that are more in-depth and easier to understand. Below are similarities and differences between the previous version of the StrateGene report and the newest version:

1. Similarities:
1. Pathway-based approach 
2. Includes Folate, Methionine, Transsulfuration, Biopterin, Histamine pathways 
3. Research-based genetic variants
4. Compounds and lifestyle activities specified to support each gene
5. Compounds and lifestyle activities that speed up or slow down each gene

1. Major differences:
1. Report data is based on Seeking Health’s custom built genetic test. No longer use 23andme or Ancestry raw data.
2. Pathways are updated with the latest research, additional genes, additional variants and simplified terminology
3. Folate and Methionine Pathways are combined into a new pathway named The Methylation Pathway. This is important as it demonstrates how these pathways work together.
4. Biopterin pathway is expanded to include the formation and recycling of biopterin
5. Dopamine, Norepinephrine and Epinephrine pathways are all greatly expanded and now exist as their own separate pathway versus being all in the Biopterin pathway
6. Serotonin and Melatonin pathways are greatly expanded and now exist as their own separate pathway versus being all in the Biopterin pathway
7. Information on what dirties specific pathways and genes
8. Recommendations on how to support specific dirty genes using lifestyle, environment, food and supplements
9. Using meters on pathways to denote if a gene is slower or faster instead of stating the presence of a variant with colors (red, yellow or green).
10. Haplotypes - researched collections of SNPs, which when in combination with each other, contribute to a specific effect such as increased susceptibility to anxiety or increased susceptibility to histamine intolerance. For example, we have a 4 SNP COMT haplotype which is way more effective than reporting just single COMT SNPs.
11. Raw data that you can browse or download on StrateGene.me
12. Ability to share your report or raw data to your physician/loved ones within a secure platform