Please see the full article link here: http://advances.nutrition.org/content/6/3/293S.full
Linoleic acid (omega 6) is not known to increase inflammation, as other omega 6 fatty acids do. A recent analysis of various studies regarding inflammation and fatty acids ("The Science of Fatty Acids and Inflammation") states that "....the often-repeated claim that dietary linoleic acid promotes inflammation was not supported in a recent systematic review of the evidence."
Furthermore it states "More often than not, higher LA intake was associated with lower, not higher, inflammatory status in healthy adults. In addition, the results from a randomized controlled trial, which was completed and published after the systematic review, indicated that increasing LA intake from 4% to 13% of energy improved (i.e., diminished) biomarkers of inflammation in obese subjects (46). Not surprisingly, those subjects consuming extra SFAs from butter showed elevations in plasma markers of inflammation.
So an important question is why did the evidence from human clinical trials fail to support the theory that dietary LA promotes inflammation? One reason might be that the “LA-proinflammatory paradigm” relies on an overly simplified model of LA metabolism. Originally, most of the proinflammatory activity of dietary LA was thought to be a consequence of an accumulation of AA, which leads to greater production and release of proinflammatory eicosanoids, such as PGE2 and leukotriene B4 (LTB4). A review of the clinical literature by Rett and Whelan (47) indicated that increasing LA up to 6-fold within the context of a typical Western diet failed to increase tissue AA. Surprisingly, reducing dietary LA down to 10% of control was without effect on circulating AA. Therefore, for those who currently advocate for large reductions in dietary LA, their emphasis has shifted to the potential adverse effects of oxidized forms of this PUFA. Recent advances in analytical capabilities (i.e., lipidomics) have greatly expanded our knowledge of LA-derived metabolites (48). Yet, our understanding of the bioactivity and physiologic role of each of these novel metabolites remains incomplete."