What is Lithium Orotate derived from? Amber Larsen April 11, 2017 20:51 Updated Follow Lithium Orotate is synthetically derived in a laboratory via the bonding of orotic acid and the alkali metal, lithium. Related articles What is the expiration date of Lithium Orotate? Are there any side-effects or precautions when using Lithium Orotate? What is the elemental amount of lithium in Lithium Orotate? Does Lithium Orotate contain corn or grain-derived ingredients? Does Lithium Orotate contain sulfur? Comments 0 comments Article is closed for comments.