What is Active B12 1000 derived from? Emily April 01, 2019 17:16 Updated Follow The adenosylcobalamin and methylcobalamin are synthetic. Related articles What is the best form of vitamin B12 for someone who is histamine intolerant? Who is Active B12 with L-5MTHF lozenge intended for? What is the difference between the Pathway Planner download and StrateGene? Why is Hydroxo B12 pink in color? What is the difference between the vitamin B12 forms methylcobalamin, adenosylcobalamin, hydroxocobalamin and cyanocobalamin? Comments 0 comments Article is closed for comments.